肝外胆管癌放疗的研究进展

Research progress of radiotherapy in extrahepatic cholangiocarcinoma

肝外胆管癌是一种较为罕见的消化系统恶性肿瘤,其复发率高,预后差。随着现代医学和放疗技术的发展,放疗联合手术、化疗、胆道支架等在可切除及不可切除的肝外胆管癌治疗过程中占据越来越重要的地位。目前已有大量研究显示外照射放疗、近距离腔内放疗、立体定向放疗等多种放疗技术具有良好的安全性和疗效,但其临床应用仍存在争议。

Extrahepatic cholangiocarcinoma is a rare,aggressive malignancy of the digestive system with high recurrence rate and poor prognosis.With the development of modern medicine and radiotherapy technology,combined with surgery,chemotherapy,and biliary stent,etc.,radiotherapy plays a more and more important role in the treatment of resectable and unresectable patients.At present,a large number of studies have shown that external beam radiotherapy,intraluminal brachytherapy,stereotactic body radiation therapy and other kinds of radiotherapy techniques have good safety and efficacy,but its clinical application is still controversial.