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丁苯酞联合口腔球囊扩张术治疗脑卒中后吞咽困难患者的疗效

Clinical Efficacy of Butylphthalide Combined with Oral Balloon Dilatation in the Treatment of Dysphagia after Stroke
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摘要 目的探讨丁苯酞联合口腔球囊扩张术治疗脑卒中后吞咽困难患者的临床疗效。方法选取2017年6月至2018年12月广州市红十字会医院收治的60例脑卒中后吞咽困难患者作为研究对象,根据治疗方式不同分为对照组(丁苯酞注射液,30例)和观察组(丁苯酞注射液+口腔球囊扩张术,30例)。比较两组患者治疗前后吞咽困难评分、日常生活能力及并发症发生率。结果治疗前,两组患者吞咽困难程度评分比较,差异无统计学意义(P>0.05);治疗后,两组患者吞咽困难程度评分明显降低,且观察组低于对照组,差异有统计学意义(P<0.05);治疗前,两组患者日常生活能力量表(ADL)评分比较,差异无统计学意义(P>0.05),治疗后,两组患者ADL评分明显升高,且观察组高于对照组,差异有统计学意义(P<0.05);观察组与对照组并发症发生率分别为6.67%、30.00%,差异有统计学意义(P<0.05)。结论丁苯酞联合口腔球囊扩张术对脑卒中后吞咽困难患者具有较好的治疗效果,不仅可减轻吞咽困难程度,减少并发症发生,还可以有效提高患者的日常生活能力。 Objective To explore the clinical effect of butylphthalide combined with oral balloon dilatation in the treatment of dysphagia after stroke.Methods A total of 60 patients with dysphagia after stroke admitted to Guangzhou Red Cross Hospital from May 2017 to May 2018 were selected as the research objects and according to different treatment methods,were divided into a control group(butylphthalide injection,30 cases)and an observation group(butylphthalide injection+oral balloon dilatation,30 cases).The scores of dysphagia,daily living ability and complication rate were compared between the two groups of patients before and after treatment.Results Before treatment,there was no significant difference in dysphagia score between the two groups(P>0.05).After treatment,the dysphagia score was significantly lower in the two groups,and the observation group was lower than the control group.(P<0.05);there was no significant difference in ADL scores between the two groups of patients before treatment(P>0.05).After treatment,the ADL scores of the two groups of patients increased significantly,and the observation group was higher than the control group(P<0.05);the incidence of complications in the observation group and the control group were 6.67%and 30.00%,respectively,and the observation group was lower,and the difference was statistically significant(P<0.05).Conclusions Butylphthalein combined with oral balloon dilatation has a better therapeutic effect on patients with dysphagia after stroke,which not only reduces the degree of dysphagia,and complications,but also effectively improves the daily living ability of patients.
作者 周慧怡 李青娉 刘文权 ZHOU Hui-Yi;LI Qing-Ping;LIU Wen-Quan(Department of Rehabilitation Medicine,Guangzhou Red Cross Hospital,Guangzhou 510000,China)
出处 《中国药物经济学》 2020年第8期56-58,共3页 China Journal of Pharmaceutical Economics
基金 2018年广州市红十字会医院内课题(2018-27)。
关键词 脑卒中 吞咽困难 丁苯酞 口腔球囊扩张术 日常生活能力 Stroke Dysphagia Butylphthalide Oral balloon dilation Daily life capacity
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