健脾贴治疗小儿肺炎后胃肠功能紊乱脾虚夹滞证75例临床观察

Clinical observation on 75 cases of gastrointestinal dysfunction with stagnation due to spleen deficiency syndrome after pediatric pneumonia treated by Jianpi Tie(健脾贴)

目的观察健脾贴治疗小儿肺炎后胃肠功能紊乱脾虚夹滞证的临床疗效。方法选取2019年2月至2020年1月福建中医药大学附属人民医院儿科门诊及住院部收治的肺炎后胃肠功能紊乱脾虚夹滞证患儿150例,采用随机数字表法分为治疗组和对照组,各75例。2组均给予肺炎的西医常规治疗,治疗组在此治疗方法的基础上给予健脾贴,对照组在此治疗方法的基础上给予酪酸梭菌肠球菌三联活菌散。2组均治疗3 d后统计临床疗效,并比较治疗前后中医证候积分的变化情况。结果治疗组总有效率为94.67%(71/75),对照组为65.33%(49/75),2组比较,差异有统计学意义(P<0.05)。治疗前,2组脘腹胀痛、不思饮食、食量减少、恶心呕吐、大便酸臭(稀溏或便秘)证候积分比较,差异均无统计学意义(P>0.05),具有可比性。治疗后,2组上述证候积分与同组治疗前比较均显著下降(P<0.05),且治疗组下降更显著(P<0.05或P<0.01)。结论健脾贴治疗小儿肺炎后胃肠功能紊乱脾虚夹滞证疗效满意,能明显改善中医证候积分,同时健脾贴不经消化道吸收,不加重肝肾代谢负担,无痛苦,患儿及家长依从性好,值得临床推广应用。

Objective To observe the clinical efficacy of Jianpi Tie(健脾贴)in the treatment of gastrointestinal dysfunction with stagnation due to spleen deficiency syndrome after pediatric pneumonia.Methods From February 2019 to January 2010,150 cases with gastrointestinal dysfunction with stagnation due to spleen deficiency syndrome after pediatric pneumonia consulted in outpatient service and admitted into in pediatric department of The People’s Hospital Affiliated to Fujian University of Chinese Medicine were divided into treatment group and control group according to random number table method,with 75 cases in each.Both groups were given routine Western medicine treatment for pneumonia,on this basis,the treatment group was given Jianpi Tie,while the control group was given clostridium butyricum TO-A.We kept statistics about the clinical efficacy after the 2 groups were both treated for 3 days and made comparison about TCM symptom scores.Results The total effective rate of the treatment group was 94.67%(71/75),that of the control group was 65.33%(49/75),and the difference was statistically significant between the 2 groups(P<0.05).Before treatment,the difference was not statistically significant in symptom scores of distention and pain of stomach and abdomen,poor appetite,reducing the feed intake,nausea and vomiting,sour and foul odor of stool(loose stool or constipation)between the 2 groups(P>0.05),and they were comparable.After treatment,the above-mentioned symptom scores of the 2 groups all significantly decreased compared with the same group before treatment(P<0.05),moreover,the treatment group decreased more significantly(P<0.05 or P<0.01).Conclusion It has satisfactory efficacy to use Jianpi Tie in the treatment of gastrointestinal dysfunction with stagnation due to spleen deficiency syndrome after pediatric pneumonia,which can obviously improve the TCM symptom score.Meanwhile,Jianpi Tie is not absorbed through the digestive tract,does not increase the burden of liver and kidney metabolism,has no pain,and has good compliance with children and parents,which is worthy of clinical promotion and application.