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瑞芬太尼复合右美托咪定在经内镜逆行胰胆管造影术中的应用效果

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摘要 目的观察瑞芬太尼复合右美托咪定在经内镜逆行胰胆管造影术(ERCP)中的应用效果。方法选取2017年4月-2018年4月福建医科大学孟超肝胆医院收治的行ERCP治疗患者50例为研究对象,采取随机数字表法分为观察组和对照组,每组25例。对照组给予丙泊酚复合右美托咪定麻醉治疗,观察组给予瑞芬太尼联合右美托咪定麻醉治疗,比较2组术前、术中麻醉警觉—镇静(OAAS)评分,2组术前1 d及术后6、12 h疼痛评分,术后满意度及不良反应。结果2组术前、术中OASS评分比较差异均无统计学意义(P>0.05);2组术前1 d疼痛评分比较差异无统计学意义(P>0.05),2组术后6、12 h疼痛评分均较术前1 d下降,且观察组疼痛评分低于对照组(P<0.01或P<0.05);观察组患者术后满意度为96.0%,高于对照组的76.0%(χ^2=4.153,P<0.05);观察组术后不良反应总发生率为8.0%,低于对照组的32.0%(χ^2=4.500,P<0.05)。结论行ERCP治疗患者给予瑞芬太尼联合右美托咪定方式进行麻醉可取得良好的麻醉效果,进一步提升患者的镇痛安全性,值得临床推广应用。
作者 林静 姚志雄
出处 《临床合理用药杂志》 2020年第23期78-79,共2页 Chinese Journal of Clinical Rational Drug Use
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