血脂水平与肺癌风险及预后相关性的研究进展

Research Progress on the Relationship between Blood Lipids and Lung Cancer Risk and Prognosis

近年来,肺癌成为导致癌症相关死亡的主要原因。越来越多证据表明,许多脂类和脂类类似物是肿瘤发生的关键调节因子,吸烟、饮食及肥胖等影响血脂水平的因素可能与癌症的风险相关。目前随着脂质与肿瘤发生过程关系的研究逐渐深入,探索血脂与肺癌风险及预后相关性已成为研究的热点。本文就血脂水平与肺癌发病风险、血脂水平与肺癌患者预后相关性及调整血脂药物与防治肺癌方向的研究进展进行综述。

In recent years,lung cancer has become the leading cause of cancer-related deaths.There is increasing evidence that many lipids and lipid analogs are key regulators of tumorigenesis,and factors that affect blood lipid levels such as smoking,diet,and obesity may be associated with cancer risk.With the deepening of research on the relationship between lipids and tumorigenesis,exploring the correlation between blood lipids and lung cancer risk and prognosis has become a research hotspot.This article reviews the research progress of the relationship between blood lipid levels and the risk of lung cancer,blood lipid levels and the prognosis of lung cancer patients,and the adjustment of blood lipid drugs and the prevention and treatment of lung cancer.