肺段切除术治疗早期非小细胞肺癌的预后研究进展

Progress in Survival Prognosis of Segmentectomy for Early-stage Non-small Cell Lung Cancer

目前手术是治疗早期非小细胞肺癌(non-small cell lung cancer,NSCLC)最好的方式,随着越来越多的单侧或双侧的多原发肺癌被发现,肺段切除术因对这类肿瘤的治疗有着独特的优势而受到广泛关注。磨玻璃为主的早期NSCLC可以通过肺段切除术获得很好的生存预后,而实性为主的NSCLC具有更高的侵袭性,其治疗手段依然存在争议。随着对肺癌的淋巴结转移途径、影像特征和分子生物学方面的深入研究,这类实性结节如果具备一定的特点也能通过肺段切除术达到根治目的。本文针对影响肺段切除术预后的因素展开综述。

Surgery is currently the most appropriate treatment for early-stage non-small cell lung cancer(NSCLC).Increasing unilateral or bilateral multiple primary lung cancer being found,segmentectomy has attracted wide attention for its unique advantages in the treatment for such tumors.Ground glass opacity dominant early-stage NSCLC is associated with a good prognosis and can be cured by segmentectomy,however,the treatment of solid-dominant NSCLC remains controversial owing to the invasive nature.With the in-depth study on the lymph node metastasis pathway,radiological characteristics and molecular biology of NSCLC,a large part of solid nodules with certain characteristics can also be cured by segmentectomy.This paper reviews the research status and progress about the indication of segmentectomy.