北京市男男性行为者HIV新发感染与检测相关性的队列研究

Relationship between HIV incidence and test among men who have sex with men in Beijing:a cohort study

目的:了解北京市男男性行为者(men who have sex with men,MSM)人类免疫缺陷病毒(HIV)新发感染与检测的相关性。方法:于2012年7月至2013年11月,在北京市招募MSM开展对列研究,进行问卷调查及HIV检测,并对其中2011年7月至12月参加HIV检测的MSM资料进行回顾性分析。结果:共招募737名符合条件的MSM,HIV新发感染率为3.4/100人年(95%CI:1.8~4.9)。多因素Logistic回归分析结果显示,最近3个月与临时性伴发生无保护性肛交(OR=4.21,95%CI:1.58~11.27)、参加过2011年检测活动(OR=2.76,95%CI:1.06~7.17)与HIV新发感染有关。结论:北京市MSM的HIV感染疫情严重,应采取有效的干预措施提高MSM检测效率,进而遏制HIV在该人群的传播。

Objective:To investigate the relationship between HIV incidence and test among men who have sex with men(MSM)in Beijing.Methods:The participants were recruited from Jul 2012 to Nov 2013 and questionnaire survey was conducted.The blood sample was tested for HIV antibodies.This study retrospectively collected the data about MSM who participated in the HIV detection from Jul 2011 to Dec 2011.Results:A total of 737 MSM were enrolled and the incidence of HIV was 3.4 per 100 person-years(95%CI:1.8-4.9).The results of the multivariable logistic regression analysis showed that unprotected anal intercourse with casual male sex partners in the last 3 months(OR=4.21,95%CI:1.58-11.27)and participation in HIV detection in 2011(OR=2.76,95%CI:1.06-7.17)were positively associated with HIV infection.Conclusions:The incidence of HIV among MSM in Beijing is serious.It is urgent to improve the efficiency of HIV detection to curb the HIV epidemic.