摘要
随着对幽门螺杆菌(Hp)感染危害认知度的提高,其根除指征不断扩大。《幽门螺杆菌胃炎京都全球共识》提出的“治疗所有Hp感染者,除非有抗衡因素”的观点已为越来越多的学者所接受,我国已将“证实有Hp感染”作为根除指征。然而,随着Hp耐药率的增加,其根除率逐渐下降,多次治疗失败者的比例不断增加。本文对Hp根除治疗相关问题进行概述,以期提高Hp感染根除率。
As the awareness of the harmfulness of Helicobacter pylori(Hp)infection increases,the indications for Hp eradication continue to expand.“Kyoto Global Consensus Report on Helicobacter pylori Gastritis”puts forward“Hp infected individuals should be offered eradication therapy,unless there are competing considerations”and the statement has been accepted by more and more scholars.In our country,“the confirmed Hp infection”has been listed as an indication for eradication.However,as the antibiotic resistance rate of Hp increases,the eradication rate of Hp is gradually decreasing,and the proportion of people who has failed multiple treatments is increasing.This article was specially written for helping the clinicians to improve the eradication rate of Hp infection.
作者
陆红
刘文忠
LU Hong;LIU Wenzhong(Division of Gastroenterology and Hepatology,Renji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai Institute of Digestive Disease,Shanghai,200001)
出处
《胃肠病学》
2020年第5期266-270,共5页
Chinese Journal of Gastroenterology
关键词
幽门螺杆菌
根除率
耐药
经验治疗
铋剂四联方案
高剂量PPI-阿莫西林二联方案
药敏试验指导的治疗
Helicobacter pylori
Eradication Rate
Drug Resistance
Empirical Therapy
Bismuth Quadruple Therapy
High-Dose PPI-Amoxicillin Dual Therapy
Susceptibility-Guided Treatment