马德龙病1例报告

A case report of Madelung’s disease

马德龙病又称为多发性对称性脂肪瘤病,是一类罕见的因脂肪代谢障碍引起的疾病,多发于30~60岁的中老年男性,主要病变特征是大量无包膜脂肪组织团块呈弥漫性、对称性聚积在颈、项、肩以及其他躯干部位的皮下组织内,目前对于该病国际上尚无标准有效的治疗方法。本文报告我科收治的1例马德龙病例,并基于现有文献资料,对马德龙病的病因、临床分型、特征性表现以及诊断、鉴别诊断和治疗等进行讨论。

Madelung’s disease, also known as multiple symmetrical lipomatosis, is a rare disease caused by fat metabolism disorders, which occurs mainly in men aged 30-60 years. The clinical feature is that a large number of non enveloped fat tissue masses are diffuse and symmetrically accumulating in the subcutaneous tissues of neck, shoulder and other regions of the body. At present, there is no standard and effective treatment for this disease in the world. This paper reported a case of Madelung’s disease. Discussed its etiology, clinical classification, characteristic manifestations,diagnosis, differential diagnosis and treatment based on the existing literature.