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基于数据挖掘探讨肝硬化腹水用药规律 被引量:5

Analysis on Medication Rule in Prescriptions for Ascites of Cirrhosis Based on Data Mining
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摘要 目的探讨肝硬化腹水的中医用药特点及规律。方法检索肝硬化腹水中医证治文献,提取医案的四诊信息,经过数据标准化处理并建立数据库,应用中医传承辅助系统挖掘其用药规律。结果本研究纳入240篇文献,医案276例。得到了治疗肝硬化腹水的核心药物为白术、赤芍、茯苓、白芍、泽泻、党参、茵陈、黄芪、猪苓、鳖甲、车前子、甘草、大腹皮、丹参,核心组合20个,并推演出新处方10个。结论疏肝理气、活血化瘀、利尿逐饮、扶正固本是治疗肝硬化腹水选药组方的核心原则。 Objective To explore the characteristics and medication rule of ascites of cirrhosis.Methods We performed a systematic search on Chinese medical literatures of ascites of cirrhosis,extracted TCM clinical information of each case and founded TCM database after standardization.TCM inheritance support system was adapted to statistic analysis.Results 240 studies and 276 cases were included in the research.The major herbs were atractylodes,radix paeoniae rubra,tuckahoe,radix paeoniae alba,rhizoma alismatis,dangshen,gall,astragalus,grifola,turtle shell,semen plantaginis,liquorice,big belly skin and salvia miltiorrhiza.20 core combinations and 10 new prescriptions were mined from the database.Conclusion The core principles of prescriptions are promoting blood circulation for removing blood stasis,promoting blood circulation for removing blood stasis,inducing diuresis to reduce fluid retention and supporting healthy energy.
作者 焦云涛 谭海成 JIAO Yuntao;TAN Haicheng(Department of spleen and stomach diseases,Shunyi Hospital,Beijing Hospital of Traditional Chinese Medicine,Beijing 101300,China)
出处 《光明中医》 2020年第18期2811-2813,2951,共4页 GUANGMING JOURNAL OF CHINESE MEDICINE
关键词 鼓胀 肝硬化腹水 中医药 数据挖掘 关联规则 聚类算法 tympanites ascites of cirrhosis traditional Chinese medicine data mining association rules clustering algorithm
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