摘要
肠神经胶质细胞是肠道神经系统的重要组成成分,不仅具有营养和支持肠神经元的作用,还能参与多种肠道功能的调控.异常活化的肠神经胶质细胞还可能是炎症性肠病、感染性肠炎、结肠癌等肠道疾病的重要致病因素之一.目前,肠神经胶质细胞在消化系统疾病中所发挥的作用尚不完全清楚,本文就这一方面的研究进展进行综述.
Enteric glial cells,as a key component of the intestinal nervous system,not only have the function of nutrition and supporting intestinal neurons,but also participate in the regulation of various intestinal functions.Abnormal activation of enteric glial cells may also be one of the important pathogenic factors for inflammatory bowel disease,intestinal infection,intestinal obstruction,colon cancer,and other intestinal diseases.At present,the role of enteric glial cells in the occurrence and development of digestive system diseases remains to be elucidated.This paper reviews the research progress in this area.
作者
王亚梅
贾漪涛
李中信
Ya-Mei Wang;Yi-Tao Jia;Zhong-Xin Li(Graduate School of Hebei Medical University,Shijiazhuang 050017,Hebei Province,China;Department of Oncology,Heibei General Hospital,Shijiazhuang 050051,Hebei Province,China;the Second Department of Surgery,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei Province,China)
出处
《世界华人消化杂志》
CAS
2020年第19期979-985,共7页
World Chinese Journal of Digestology
关键词
肠神经胶质细胞
肠道黏膜屏障
免疫调节
肠道动力
肠道疾病
Enteric glial cells
Intestinal epithelial barrier
Intestinal immunity
Intestinal motility
Intestinal diseases