不同血液净化方法治疗重症急性肾功能衰竭的临床疗效

Clinical Observation of Different Blood Purification Methods in the Treatment of Severe Acute Renal Failure

目的探究在重症急性肾功能衰竭的临床治疗中,不同血液净化方法的治疗效果。方法选取2017年4月至2018年4月在我院接受治疗的重症急性肾功能衰竭患者中的50例进行此次研究,回顾性分析所有研究对象的临床资料,按照奇偶法将研究对象分成对照组和观察组,每组患者25例。对照组实施间歇性血液透析治疗,观察组实施连续性血液净化治疗,对比两组患者的临床疗效及凝血功能、血流动力学、生化指标的改变情况。结果治疗前两组患者的血肌酐、血尿氮素指标对比无明显差异(P> 0.05),治疗后观察组患者的临床疗效高于对照组,血肌酐、血尿氮素生化指标优于对照组,组间差异均存在统计学意义(P <0.05)。结论不同血液净化治疗方法在重症急性肾功能衰竭患者中的治疗效果不同,连续性血液净化对于重症急性肾功能衰竭患者的临床应用价值更高,值得进一步的推广使用。

Objective To explore the therapeutic effects of different blood purification methods in the clinical treatment of severe acute renal failure.Methods Fifty patients with severe acute renal failure treated in our hospital from April 2017 to April 2018 were selected for this study.The clinical data of all the subjects were analyzed retrospectively.The subjects were divided into control group and observation group according to the odd-even method,with 25 patients in each group.The control group was treated with intermittent hemodialysis,while the observation group was treated with continuous blood purifi cation.The clinical effi cacy and changes of coagulation function,hemodynamics and biochemical indexes were compared between the two groups.Results Before treatment,there was no signifi cant diff erence in serum creatinine and hematuria nitrogen index between the two groups(P>0.05).After treatment,the clinical effi cacy of the observation group was higher than that of the control group,and the biochemical indexes of serum creatinine and hematuria nitrogen were better than that of the control group,with statistical diff erences between the two groups(P<0.05).Conclusion Diff erent blood purifi cation methods have diff erent therapeutic eff ects in patients with severe acute renal failure,and continuous blood purifi cation has higher clinical application value for patients with severe acute renal failure,which is worthy of further promotion.