硝普钠与酚妥拉明急诊治疗冠心病合并心力衰竭的临床疗效评价

Evaluation of clinical efficacy of sodium nitroprusside and phentolamine in emergency treatment of coronary heart disease with heart failure

目的:研究硝普钠与酚妥拉明用于冠心病合并心力衰竭患者急诊治疗的临床效果。方法:2018年9月-2019年9月急诊收治冠心病合并心力衰竭患者70例,随机分为两组,各35例。对照组采用甲磺酸酚妥拉明治疗;观察组采用硝普钠治疗。比较两组临床疗效。结果:观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组左心室射血分数(LVEF)、左心室收缩末期内径(LVEFSD)以及左心室舒张末期内径(LVEFDD)水平均明显优于对照组,差异有统计学意义(P<0.05)。结论:与酚妥拉明相比,硝普钠用于冠心病合并心力衰竭患者的急诊治疗效果更理想,对患者心功能的改善效果更好。

Objective:To study the clinical effect of sodium nitroprusside and phentolamine in emergency treatment of patients with coronary heart disease complicated with heart failure.Methods:From September 2018 to September 2019,70 patients with coronary heart disease complicated with heart failure were selected,they were randomly divided into the two groups with 35 cases in each group.The control group was treated with phenytol mesylate lemine.The observation group was treated with sodium nitroprusside.The clinical effects of the two groups were compared.Results:The total effective rate in the observation group was significantly higher than the control group,the difference was statistically significant(P<0.05).The levels of left ventricular ejection fraction(LVEF),left ventricular end-systolic diameter(LVEFSD)and left ventricular end-diastolic diameter(LVEFDD)in the observation group were significantly better than those in the control group,the difference was statistically significant(P<0.05).Conclusion:Compared with phentolamine,sodium nitroprusside is more effective in emergency treatment of patients with coronary heart disease complicated with heart failure.