慢性阻塞性肺疾病临床表型与炎症水平相关性的研究

Study on the relationship between clinical phenotype and inflammatory level in patients with chronic obstructive pulmonary disease

目的:研究慢性阻塞性肺疾病临床表型与炎症水平相关性。方法:2017年1月-2019年12月收治慢性阻塞性肺疾病患者122例。分析临床表型与炎症间的关系。结果:慢支型、肺气肿型、哮喘-慢性阻塞性肺疾病重叠(ACO)型C反应蛋白(CRP)、血沉(ESR)、降钙素原(PCT)与比较,差异有统计学意义(P<0.05)。结论:炎症因子水平对慢支型、肺气肿型、ACO型慢性阻塞性肺疾病患者的临床诊断具有一定的辅助作用,可被当作患者炎性水平的评估参考指标。

Objective:To study the relationship between clinical phenotype and inflammatory level of chronic obstructive pulmonary disease(COPD).Methods:From January 2017 to December 2019,122 patients with chronic obstructive pulmonary disease were selected.The relationship between clinical phenotype and inflammation was analyzed.Results:There were significant differences in C-reactive protein(CRP),erythrocyte sedimentation rate(ESR)and procalcitonin(PCT)among chronic bronchitis,emphysema,asthma chronic obstructive pulmonary disease overlap(ACO),the differences were statistically significant(P<0.05).Conclusion:The level of inflammatory factors plays an auxiliary role in the clinical diagnosis of chronic obstructive pulmonary disease patients with chronic bronchitis,emphysema and ACO,and can be used as a reference index to evaluate the level of inflammation in patients.