西地兰联合米力农治疗慢性心力衰竭的效果探讨

Discussion on the effect of cedilanid combined with milrinone in the treatment of chronic heart failure

目的:研究西地兰联合米力农治疗慢性心力衰竭的临床效果。方法:2018年1月-2020年2月收治慢性心力衰竭患者40例,随机分为两组,各20例。对照组采用米力农治疗;观察组采用西地兰联合米力农治疗。比较两组临床疗效、不良反应发生情况、心功能指标复常时间、心电图表现复常时间、住院总时间及心功能指标水平。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,观察组心功能指标复常时间、心电图表现复常时间、住院总时间均短于对照组,观察组治疗后心功能指标水平改善幅度优于对照组,差异均有统计学意义(P<0.05)。结论:慢性心力衰竭患者采用西地兰联合米力农进行治疗,能减少药物不良反应,在短时间内大幅度改善心功能指标,缩短治疗时间,使治疗总有效率得到显著提升。

Objective:To study the clinical effect of cediland combined with milrinone in the treatment of chronic heart failure.Methods:From January 2018 to February 2020,40 patients with chronic heart failure were selected,they were randomly divided into the two groups with 20 cases in each group.The control group was treated with milrinone.The treatment group was treated with cediland and milrinone.The total effective rate of drug treatment,adverse drug reactions,cardiac function index recovery time,ECG performance recovery time,total hospitalization time and cardiac function index level were compared.Results:The total effective rate of the treatment group was higher than the control group,with significant difference(P<0.05).Compared with the control group,the incidence of adverse reactions in the observation group was lower,and the time for the normalization of cardiac function,the time for the normalization of ECG and the total time of hospitalization in the observation group were shorter than the control group,the improvement of cardiac function index after treatment in the observation group was better than the control group,the difference was statistically significant(P<0.05).Conclusion:The treatment of chronic heart failure patients with cediland combined with milrinone can reduce the adverse drug reactions,significantly improve the cardiac function index in a short time,shorten the treatment time,and significantly improve the total effective rate of treatment.