湖北省市售鸡蛋鸡肉中甲硝唑及禁用药物残留监测分析

Analysis of metronidazole and prohibited drug residues in chicken and eggs sold in Hubei Province

目的了解湖北省禽肉禽蛋中甲硝唑及禁用药物残留水平。方法在湖北省13个市州和潜江市、仙桃市的大型超市和农贸市场采集市售鸡肉及鸡蛋样品168件,采用超高效液相色谱-质谱法检测甲硝唑及利巴韦林、金刚烷胺、金刚乙胺的残留量。结果金刚烷胺、利巴韦林、金刚乙胺未检出,甲硝唑检出率4.17%(7/168)。甲硝唑不同年份间检出率差异有统计学意义,但无随年度增加或减少的趋势;禁用药物不同年份间检出率差异有统计学意义(P<0.05),并有随年度减少的趋势。结论湖北省部分地区鸡蛋、鸡肉养殖业仍存在甲硝唑违规使用的现象,需要引起相关部门关注和重视。

Objective To investigate the level of metronidazole and prohibited drug residues in poultry meat and eggs in Hubei Province.Methods A total of 168 chicken and egg samples were collected from 13 prefecture level cities and autonomous prefectures of Hubei Province,Qianjiang City and Xiantao City.The residues of metronidazole,ribavirin,amantadine and rimantadine were determined by ultra performance liquid chromatography-mass spectrometry.Results Amantadine,ribavirin and rimantadine were not detected.The detection rate of metronidazole was 4.17%(7/168).There was significant difference in the detection rate of metronidazole in different years,but there was no trend of increase or decrease with the year;the difference of detection rate of banned drugs in different years was statistically significant,and had a trend of decreasing with the year.Conclusion The illegal use of metronidazole still exists in some areas of Hubei Province,which needs to be paid attention to by relevant departments.