Smart nanoprobe based on two-photon sensitized terbium-carbon dots for dual-mode fluorescence thermometer and antibacterial

Accurate temperature measurement plays an important role in a variety of industrial processes and scientific researches.In our work,the dual-mode temperature response nanoprobe CDs-Tb-TMPDPA containing a two-photon ligand(4-(2,4,6-trimethoxyphenyl)-pyridine-2,6-dicarboxylic acid,TMPDPA)sensitized Tb3+as a temperature-sensitive unit and carbon dots(CDs)as photothermal reagent and a fluorescence reference unit,have been designed and synthesized.In this system,both the fluorescence intensity ratio and the fluorescence lifetime have a good response to temperature.In additio n,due to the excellent photothermal conversion capability of CDs,photothermal antibacterial ability was also tested.Based on the temperature dependence of the fluorescence and the two-photon excitation characteristics of CDs-Tb-TMPDPA,the nanoprobe can also be used in the anti-counterfeiting.Our finding opens a new prospect for the use of two-photon sensitized dual-mode fluorescence thermometers.