摘要
A TFA promoted multi-component reaction of aryldiazonium with sodium metabisulphite and thiols to construct thiosulfonates under transition-metal free conditions is reported.The thiosulfonates were isolated in good yields with broad tolerance of functional group.Readily available inorganic Na2S2O5 was applied as the sulfur dioxide surrogate.This strategy features easily available substrates,mild reaction conditions and free transition-metal catalyst.
基金
the National Natural Science Foundation of China(Nos.21971174,21772137,21672157)
the PhD Programs Foundation of PAPD
the Project of Scientific and Technologic Infrastructure of Suzhou(No.SZS201708)
the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(No.16KJA150002)
Soochow University,and State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials for financial support。
