早期宫颈癌保留生育功能的保守性手术的肿瘤预后及妊娠结局

Prognosis and obstetrical outcomes of patients with early cervical cancer after fertility-sparing coservative surgery

随着宫颈癌筛查技术的普及,越来越多的宫颈癌患者在早期被发现。并且宫颈癌发病日益趋向于年轻化。大多数生育年龄的宫颈癌患者有强烈的保留生育功能意愿。近年来,根治性手术作为早期宫颈癌的标准治疗方案受到挑战,因其伴广泛宫旁切除导致手术并发症高。早期宫颈癌的治疗指向更为保守的手术方式,如宫颈锥切术、简单的宫颈切除术,可以减少术后病率而不损害肿瘤安全性和早期疾病患者的生殖潜力。文章对早期宫颈癌保留生育的保守性手术的肿瘤结局及妊娠结局做一概述。

There is a rising incidence of early cervical cancer in young patients due to widespread diffusion of screening programs.Most childbearing age women with cervical cancer wish to preserve their fertility.Radical surgery is associated with several complications,primarily owing to the removal of the parametria,and recently many findings have challenged the necessity of radical hysterectomy for patients with early-stage cervical cancer.In recent years,more conservative methods of fertility sparing have become an accepted treatment,including cervical conization,simple trachelectomy,which can reduce surgical morbidity without affecting the chances of cure and reproductive potential.By reviewing the related literature,we discuss the oncological and pregnancy outcomes of conservative fertility-sparing surgery in patients with early-stage cervical cancer.