针灸调节胃肠动力机制的研究进展与思考

Research advances in the mechanism of acupuncture and moxibustion in regulating gastrointestinal motility and related thinking

胃肠动力功能异常既是发病因素,又是病理表现。笔者对近年针灸调节胃肠动力机制的相关研究进行分析与总结,发现针灸通过对脑-迷走神经-肠神经系统、Cajal间质细胞、胃肠肽、胃肠平滑肌及信号通路的调节改善胃肠动力。围绕胃肠动力功能,未来应开展针灸调节胃肠动力防治疾病的研究、腧穴特异性的研究、针灸双向调节的研究;针对针灸对肠道微生物群、肠神经元兴奋性影响因素的调控,开展研究探索针灸调节胃肠动力功能的潜在机制,以期为今后的研究提供参考与借鉴。

Gastrointestinal motility dysfunction is not only a pathogenic factor but also a pathological manifestation.The authors summarize the recent studies on the mechanism of acupuncture and moxibustion in regulating gastrointestinal motility and analyze the effect of acupuncture and moxibustion on the brain-vagus-enteric nervous system,interstitial cells of Cajal,gastrointestinal peptides,gastrointestinal smooth muscle,and signaling pathways.The authors also put forward some suggestions for future research,including the research centering on gastrointestinal motility to explore the role of acupuncture and moxibustion in regulating gastrointestinal motility for disease prevention and treatment,specificity of acupoints,and dual-directional regulation of acupuncture and moxibustion,and the research focusing on intestinal microflora and influential factors for excitability of enteric neurons to explore the potential mechanism of acupuncture and moxibustion in regulating gastrointestinal motility,in order to provide a reference for future research.