遵化市原发性甲状腺功能减退症患者维生素D水平调查分析

Investigation and Analysis of Vitamin D Level in Patients with Primary Hypothyroidism in Zunhua City

目的了解遵化市人民医院就诊的原发性甲状腺功能减退症患者的25-羟维生素D水平,为治疗和预防原发性甲状腺功能减退症患者的维生素D缺乏及不足提供科学依据。方法选取2019年5月至2020年1月遵化市人民医院收治的原发性甲状腺功能减退症患者337例作为研究对象,利用荧光免疫层析法检测其血清25-羟维生素D的水平,以了解患者维生素D的营养状况。结果25-羟维生素D缺乏组占40.06%(135/337),25-羟维生素D不足组占50.45%(170/337),共占90.50%(305/337);25-羟维生素D充足组占9.50%(32/337)。结论遵化市原发性甲状腺功能减退症患者存在较为严重的25-羟维生素D缺乏及不足,应加强对甲状腺功能减退症患者维生素D营养知识的系统教育,及时补充维生素D。

Objective To provide scientific basis for the prevention and treatment of vitamin D deficiency in clinical hypothyroidism patients,and this study provides a scientific basis for the treatment and prevention of vitamin D deficiency in patients with primary hypothyroidism.Methods Totally 337 patients with primary hypothyroidism to the Zunhua People's Hospital from May 2019 to January 2020 were selected as the study object.The serum level of 25-hydroxyvitamin D was detected by fluorescence immunochromatography to understand the nutritional status of vitamin D.Results Among 337 patients,40.06%(135/337)were in the 25-hydroxyvitamin D deficiency group,50.45%(170/337)in the 25-hydroxyvitamin D deficiency group,90.50%(305/337)in the 25-hydroxyvitamin D deficiency group,and 9.50%(32/337)in the 25-hydroxyvitamin D sufficiency group.Conclusion The nutritional status of 25-hydroxyvitamin D in patients with primary hypothyroidism in Zunhua city is very poor.We should strengthen the systematic education of vitamin D nutrition knowledge for hypothyroidism patients and supply vitamin D in time.