产前超声诊断Pierre Robin序列征

Prenatal diagnosis of Pierre Robin sequence by ultrasound

目的探讨Pierre Robin序列征的产前超声声像图特征和诊断方法。方法对2017年1月至2020年1月深圳市妇幼保健院产前超声诊断的12例Pierre Robin序列征胎儿的图像特征进行分析,并与产后结果进行对照研究,收集染色体检查结果。结果12例Pierre Robin序列征胎儿产前超声特征均表现为小下颌、不完全腭裂、舌后坠,其中单纯Pierre Robin序列征4例,合并其他畸形8例。漏诊1例,为单纯Pierre Robin序列征。结论Pierre Robin序列征在产前具有特征性声像表现,经颜面矢状切面和经口裂腭斜冠状切面扫查对诊断具有重要价值。

Objective To explore the characteristics and diagnostic methods of Pierre Robin sequence in prenatal ultrasonography.Methods The ultrasonographic features and pregnancy outcome were analyzed in 12 cases of fetuses with Pierre Robin sequence who were diagnosed by ultrasound prenatally in Shenzhen Maternity&Child Healthcare Hospital from 2017 January to 2020 January,and chromosome examination results were collected.Results Prenatal ultrasonographic features of 12 cases of Pierre Robin sequence were characterized by micrognathia,incomplete cleft palate and tongue posture,among which 4 cases were isolated Pierre Robin sequence,8 cases were combined with associated malformations,and 1 case of isolated Pierre Robin sequence was misdiagnosed.Conclusions Fetus with Pierre Robin sequence has characteristic features in prenatal ultrasound,the facial median sagittal plane and oblique coronal plane of palate through oral cleft are contributive to its diagnosis.