脂质对皮肤状态的影响及对相关化妆品研发的指导

Effects of lipids on skin condition and guidance on the development of related cosmetics

皮肤脂质通过不同的机制显著影响皮肤状态,进一步的研究需要使用脂质组学——一种更强大高通量、高分辨率的脂质分析工具,全面鉴定数千种皮肤脂质成分。通过对脂质结构和功能的验证,以研究单个脂质组分对皮肤状态的影响。文章从物理化学、生物化学、微生态3个功能方面综述皮肤脂质对皮肤状态的作用及其机制,并对脂质组学数据如何促进皮肤脂质对皮肤状态影响机制的研究进行阐述,指导相关化妆品的研发。

Skin lipids dramatically influence the skin condition by different mechanisms.Further research needs the use of lipidomics which has more powerful analytical ability and high-throughput manner,to identify skin lipid components into individual species.The validation of structure and function of lipids was operated to study the process that individual lipid species was involved in.The effects and mechanisms of skin lipids on skin conditions were reviewed from three aspects of functions in physical chemistry,biochemistry and microecology.Additionally,the integration of lipidomics data with other omics strategies could develop the power to study the mechanism of skin lipids influencing skin condition,which could guide the relevant research and development of cosmetics.