摘要
BACKGROUND Chronic kidney disease(CKD)affects almost 3%of females of child-bearing age,who have a high risk of adverse maternal and fetal outcomes.Additionally,high renal burden as a result of pregnancy may lead to deterioration of renal function.An increasing number of women with CKD stages 3 to 5 have a strong desire to conceive,and both obstetricians and nephrologists are faced with enormous challenges in terms of their treatment and management.CASE SUMMARY The case of a 35-year-old pregnant woman with a 10-year history of mild mesangial proliferative glomerulonephritis is described here.CKD progressed from stage 3 to stage 5 rapidly during pregnancy,and protective hemodialysis was started at 28 wk of gestation.Due to preeclampsia at 34 wk of gestation,cesarean section was performed and a healthy baby was delivered.Hemodialysis was discontinued at 4 wk postpartum.After 1 year of follow-up,her renal function was stable,and her baby exhibited good growth and development.CONCLUSION Protective hemodialysis during pregnancy can prolong gestational age and improve maternal and fetal outcomes in women with advanced CKD.
