子宫厚度对PCOS冻胚移植周期妊娠结局的影响

Effect of uterine thickness on pregnancy outcomes of frozen embryo transfer in PCOS patients

回顾性分析258例多囊卵巢综合征(PCOS)患者和604例对照组,分析子宫厚度对PCOS患者足月产的预测价值及其相关影响因素。PCOS组与对照组相比,子宫厚度较薄,足月产率降低(P<0.05)。子宫厚度对PCOS患者足月产预测的ROC曲线下面积(AUC)为0.719(95%CI:0.657-0.781,P<0.001),临界值为34.5 mm,年龄与子宫厚度呈正相关(P<0.001),而基础睾酮与子宫厚度呈负相关(P=0.033)。PCOS患者冻胚移植日子宫厚度较薄,是影响PCOS患者足月产率的一个重要因素,对PCOS患者足月产率有一定的预测价值。

A retrospective analysis of 258 polycystic ovary syndrome(PCOS) patients and 604 control persons was conducted to analyze the predictive value of uterus thickness on term delivery of PCOS patients and its related factors. Compared with the control group, the uterus thickness of PCOS group was significantly smaller than that of the control group, and the term delivery rate was significantly lower(P<0.05). The area under the ROC curve(AUC) of uterine thickness predicted for the term delivery of PCOS patients was 0.719(95% CI: 0.657-0.781, P<0.001). The cut-off value of uterus thickness was 34.5 mm. There was a significant positive correlation between age and uterus thickness(P<0.001), while there was a significant negative correlation between basal testosterone and uterus thickness(P=0.033) in PCOS patients. The thickness of uterus in PCOS patients is significantly thinner than that in the control group. Uterus thickness is an important factor affecting the term delivery rate of PCOS patients. It has a certain predictive value for the term delivery rate of PCOS patients.