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双同态病原体的进化动力学模型研究

Evolutionary Dynamics of Bihomomorphic Pathogen Virulence
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摘要 基于适应动力学等方法去研究病原体的毒性进化,可以为传染病治疗方法的设计和防控策略的制定提供定量参考和有效的建议。从典型的传播动力学模型出发,利用动力系统理论和进化动力学理论等方法研究了双同态病原体毒性特征的进化机制,得到其进化稳定和收敛稳定的条件,并通过数值模拟验证了在具体的权衡函数条件下,双同态病原体进化稳定共存的进化现象。 Based on adaptive kinetics to study the interaction between the host and pathogens lead to viral toxicity evolutionary,Which can provide some quantitative reference and effective suggestions for the design of disease treatment methods and the development of prevention and control strategies.Based on the typical propagation dynamics model,this paper studies the The evolutionary mechanism of the toxicity characteristics of the bihomomorphic pathogen was studied,and the conditions for its evolutionary stability and convergence stability were obtained.Numerical simulation is used to verify the stable coexistence of two homomorphic pathogens under the condition of specific tradeoff functions.
作者 原博 Yuan Bo(Shanxi engineering vocational college,shanxi Taiyuan 030009)
出处 《生物化工》 2020年第5期52-56,64,共6页 Biological Chemical Engineering
关键词 适应动力学 临界函数分析法 进化稳定共存 进化动力学模型 Adaptive dynamics Critical function analysis Virulence evolution Evolutionary stable coexistence Evolutionary dynamics model
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