31例新型冠状病毒肺炎患者的静脉血栓栓塞症预防策略研究

Thromboprophylaxis of 31 patients with COVID-2019

目的探讨新型冠状病毒肺炎患者的静脉血栓栓塞症(VTE)预防策略。方法回顾性分析武汉大学中南医院重症病区2020年2月17日至3月10日收治的31例感染新型冠状病毒肺炎患者的临床资料,分析患者的基础信息、临床表现、检验检查、用药情况和Padua评分,将5G远程超声诊断系统应用于双下肢静脉、下腔静脉和心脏超声检查,根据患者情况制定V TE防控策略,观察患者VTE发生率。结果31例患者中普通型20例,重症11例;所有患者均经过动态评估、制定VTE防控策略,28例患者采用基本预防,3例患者采用机械预防。所有患者住院期间无VTE事件的发生。结论VTE的预防和监控在新型冠状病毒肺炎患者的救治中是不可忽视的环节,在有限的条件下,严密的临床观察、动态的风险评估和积极的干预措施能够有效地降低下肢深静脉血栓的形成,预防致死性肺动脉栓塞的发生。

Objective To investigate thromboprophylaxis of patients with COVID-19.Methods Clinical data of 31 patients with COVID-19 in Zhongnan Hospital of Wuhan University was analyzed retrospectively,including basic information,clinical characteristics,examination results,therapy and Padua scores.5G remote ultrasound diagnosis system was used in the ultrasonography of lower limb vein,inferior vena cava and the heart.According to the patient's status,the thromboprophylaxis was established,and the incidence of venous thromboembolism(VTE)was observed.Results There were 20 cases of general types and 11 cases of severe types.All patients underwent dynamic assessment and thromboprophylaxis.Basic prevention was applied in 28 cases and mechanical prevention was used in 3 cases.There was no VTE event in all patients during hospitalization.Conclusions Prevention and monitoring of VTE is an important part of the treatment of patients with COVID-19,which can effectively reduce the incidence of lower extremity deep vein thrombosis and fatal pulmonary embolism in isolation ward.