氢氟酸吸入性损伤的诊断及治疗研究进展

Research advances on the diagnosis and treatment of hydrofluoric acid inhalation injury

氢氟酸吸入性损伤虽发病率较低,但治疗棘手,轻者咳嗽、咽痛,重者可发展为急性呼吸窘迫综合征危及生命,还可导致罕见的肺部疾病如反应性气道功能障碍综合征及肺泡蛋白沉积症。目前对氢氟酸吸入性损伤尚无明确的诊疗规范,笔者通过查阅国内外有关文献,总结了氢氟酸吸入性损伤的发病率、致伤机制、临床诊断及治疗,并提出脉搏轮廓心输出量监测及体外膜氧合呼吸支持治疗重症患者有较大的应用前景,以供同行参考。

Hydrofluoric acid inhalation injury is difficult to treat,despite it has low incidence.It could cause mild symptoms such as cough and sore throat,or severe symptom that may develop into life-threatening acute respiratory distress syndrome,and even rare pulmonary diseases such as reactive airway dysfunction syndrome and pulmonary alveolar proteinosis.Currently,there is no specific standard for the diagnosis and treatment of hydrofluoric acid inhalation injury.Authors summarize the incidence,injury mechanism,clinical diagnosis and treatment of hydrofluoric acid inhalation injury by searching literature at home and abroad and propose that pulse contour cardiac output monitor and extracorporeal membrane oxygenation have great application prospects in treatment of severe cases,so as to provide references for peers.