中药灌胃联合芒硝外敷对重症加强护理病房重症急性胰腺炎患者的治疗效果分析

An analysis of the therapeutic effects of TCM medicine gavage plus external application of Glauber’s salt on ICU patients with severe acute pancreatitis

目的:采取中西医结合内科治疗的方法对重症加强护理病房(Intensive Care Unit,ICU)重症急性胰腺炎进行治疗并观察其疗效。方法:随机选取自2017年7月-2019年1月来我院收治的64例ICU重症急性胰腺炎患者,分成两组,每组32例。对照组:采取常规西医内科治疗;观察组:在西医治疗外加用中药灌胃和芒硝外敷。观察两组各项临床指标,对比两组的治疗效果。结果:治疗后,观察组的生命体征稳定时间(3.31±1.25)d、症状改善时间(3.52±1.45)mL、肠鸣音恢复时间(12.35±5.75)d及ICU住院时间(4.17±1.21)d均短于对照组(P<0.05);观察组C-反应蛋白(C-reactive Protein,CRP)和血清淀粉酶的水平变化明显较对照组优(P<0.05);观察组的治疗总有效率显著高于对照组,且各项并发症的发生率均较对照组低(P<0.05)。治疗前,对照组和观察组的白细胞介素-6(Interleukin-6,IL-6)差异无统计学意义(P>0.05),治疗后,两组患者的IL-6、肿瘤细胞坏死因子(Tumor Necrosts Factor,TNF-α)水平均显著低于对照组,差异有统计学意义(P<0.05)结论:对ICU重症急性胰腺炎采取中西医结合内科治疗,能够有效提高疗效,降低并发症发生率,效果显著,有临床意义,值得推广。

Objective:To observe the therapeutic effect of the integrative medicine on severe acute pancreatitis in the ICU.Methods:64 cases were randomly selected and divided into 2 groups,32 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated by TCM medicine gavage plus external application of Glauber’s salt more.Results:After treatment,the observation group’s vital signs stable time,symptom improvement time,bowel sound recovery time,and ICU hospital stay time were shorter than the control group(P<0.05).The changes in the levels of CRP and serum amylase in the observation group were significantly better than those in the control group(P<0.05).The efficiency in the observation group significantly higher than the control group,and the incidence of various complications were lower than the control group(P<0.05).After treatment,the IL-6 and TNF-αin two groups were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Treating severe acute pancreatitis in ICU in the integrative medicine can reduce the incidence of complications.The effect is significant and clinically meaningful,and it is worthy of promotion.