闭合复位空心钉内固定术和全髋关节置换术对创伤性股骨颈骨折患者预后的影响

Effects of closed reduction and cannulated screw internal fixation and total hip arthroplasty on the prognosis of patients with traumatic femoral neck fractures

目的探讨闭合复位空心钉内固定术和全髋关节置换术对创伤性股骨颈骨折患者预后的影响。方法选择本院2019年1月17日至2019年12月9日收治的84例创伤性股骨颈骨折患者作为研究对象,采用机械取样法将其分为观察组(42例,闭合复位空心钉内固定术)与对照组(42例,全髋关节置换术)。比较两组的治疗效果。结果术后12周,两组的ALP、BGP、OPG水平均升高,CRP、IL-1、TNF-α水平均降低,且观察组优于对照组(P<0.05)。观察组术后EQ-5D总分显著高于对照组,并发症总发生率低于对照组(P<0.05)。结论闭合复位空心钉内固定术治疗创伤性股骨颈骨折,可改善患者的骨形成标志物及炎性因子水平,提升生存质量,且安全性较高,值得临床推广使用。

Objective To investigate the effects of closed reduction and cannulated screw internal fixation and total hip arthroplasty on the prognosis of patients with traumatic femoral neck fractures.Methods A total of 84 patients with traumatic femoral neck fracture admitted in our hospital from January 17,2019 to December 9,2019 were selected as the research objects.The patients were divided into observation group(42 cases,closed reduction and cannulated screw internal fixation)and control group(42 cases,total hip arthroplasty)by mechanical sampling method.The therapeutic effects of the two groups were compared.Results At 12 weeks after operation,the levels of ALP,BGP and OPG in the two groups increased,and the levels of CRP,IL-1 and TNF-αdecreased,and those in the observation group were better than the control group(P<0.05).The postoperative EQ-5D total score of the observation group was significantly higher than that of the control group,and the total incidence of complications was lower than that of the control group(P<0.05).Conclusion Closed reduction and cannulated screw internal fixation in the treatment of traumatic femoral neck fractures can improve the levels of bone formation markers and inflammatory factors in patients,promote the quality of life,and has high safety,which is worthy of clinical promotion and application.