高强度聚焦超声治疗子宫腺肌瘤消融率的影响因素分析

Analysis of Factors Affecting the Ablation Rate of Uterine Adenomyoma Treated by High-intensity Focused Ultrasound

目的探讨影响高强度聚焦超声治疗子宫腺肌瘤消融率的相关因素。方法选取我院2018年1~12月因子宫腺肌瘤进行高强度聚焦超声治疗的77例患者作为研究对象,计算治疗消融率,根据治疗消融率分为A、B两组,A组(消融率>50%)患者55例,B组(消融率≤50%)患者22例,比较两组临床及随访资料,分析影响子宫腺肌瘤消融率的相关因素。结果单因素分析显示,不同肌瘤位置、年龄、是否出现团块、腹壁瘢痕、腺肌瘤位置的患者子宫腺肌瘤消融率比较,差异无统计学意义(P>0.05);不同肿瘤直径、治疗强度的子宫腺肌瘤消融率比较,差异有统计学意义(P<0.05);多因素回归分析显示,消融率与肌瘤直径、治疗强度密切相关,肌瘤位置对消融率也有一定的影响,而年龄、是否出现团块、腹壁瘢痕、腺肌瘤位置均对子宫腺肌瘤消融率无影响。结论子宫腺肌瘤的治疗强度、大小、位置均会对消融产生影响,对相关因素进行干预能够提高消融率,从而改善治疗效果。

Objective To investigate the related factors affecting the ablation rate of uterine adenomyoma treated by high-intensity focused ultrasound.Methods 77 patients who underwent high-intensity focused ultrasound treatment for adenomyoma from January to December 2018 in our hospital were selected as the research object,and the treatment ablation rate was calculated.According to the treatment ablation rate,they were divided into two groups A and B,there were 55 patients in group A(ablation rate>50%)and 22 patients in group B(ablation rate≤50%).The clinical and follow-up data of the two groups were compared,and related factors affecting the ablation rate of adenomyoma were analyzed.Results Univariate analysis showed that there was no statistically significant difference in the ablation rate of adenomyoma among patients with different fibroids,age,mass,abdominal wall scars,and adenomyoma locations(P>0.05);different tumor diameters,comparison of the ablation rate of uterine adenomyoma with treatment intensity was statistically significant(P<0.05);multivariate regression analysis showed that the ablation rate was closely related to the diameter of the fibroids and the treatment intensity,and the location of the fibroids also has a certain influence on the ablation rate,however,age,presence of masses,abdominal wall scars,and adenomyoma location had no effect on the ablation rate of adenomyoma.Conclusion The treatment intensity,size and location of uterine adenomyoma would affect the ablation.Intervention of related factors could increase the ablation rate and improve the treatment effect.