悬雍垂腭咽成形术联合持续正压通气治疗阻塞性睡眠呼吸暂停低通气综合征患者的效果

Uvulopalatopharyngoplasty Combined with Continuous Positive Pressure Ventilationin the Treatment of Patients with Obstructive Sleep Apnea Hypopnea Syndrome

目的探讨悬雍垂腭咽成形术联合持续正压通气(CPAP)治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的临床疗效。方法选择我院2018年7月~2019年7月收治的OSAHS患者85例作为研究对象,按照随机数字表法分为观察组(n=43)和对照组(n=42)。对照组给予悬雍垂腭咽成形术治疗,观察组在对照组基础上给予CPAP治疗,比较两组临床疗效、嗜睡评分、最长呼吸暂停时间、呼吸暂停低通气指数及QSQ评分。结果观察组治疗总有效率为95.35%,高于对照组的78.57%,差异有统计学意义(P<0.05)。治疗后,观察组嗜睡评分、最长呼吸暂停时间、呼吸暂停低通气指数低于对照组,差异有统计学意义(P<0.05)。观察组白天嗜睡、白天症状、夜间症状、情绪、社会交往及QSQ总分高于对照组,差异有统计学意义(P<0.05)。结论悬雍垂腭咽成形术联合CPAP治疗OSAHS疗效确切,可有效降低嗜睡评分,缩短最长呼吸暂停时间及呼吸暂停低通气指数,优化睡眠结构,提高睡眠及生活质量。

Objective To investigate the clinical effect of uvulapalatopharyngoplasty combined with continuous positive pressure(CPAP)in the treatment of patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods A total of 85 OSAHS patients admitted to our hospital from July 2018 to July 2019 were selected as the research objects,and were divided into observation group(n=43)and control group(n=42)according to the random number table method.The control group was treated with uvulapalatopharyngoplasty,and the observation group was treated with CPAP on the basis of the control group.The clinical efficacy,sleepiness score,longest apnea time,apnea hypopnea index and QSQ score were compared between the two groups.Results The total effective rate of treatment in the observation group was 95.35%,which was higher than 78.57%in the control group,the difference was statistically significant(P<0.05).After treatment,the sleepiness score,maximum apnea time,and apnea hypopnea index of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).The total scores of daytime sleepiness,daytime symptoms,nighttime symptoms,mood,social interaction and QSQ in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05).Conclusion Uvulopalatopharyngoplasty combined with CPAP was effective in the treatment of OSAHS.It could effectively reduce the sleepiness score,shorten the maximum apnea time and apnea hypopnea index,optimize sleep structure,and improve sleep and quality of life.