支气管扩张共病患病风险及对预后的影响

Research Progress in Comorbidity Risk and Influence on Prognosis of Bronchiectasis

支气管扩张的特征是慢性全身炎症,通常与合并症共存,包括心脑血管疾病、慢性阻塞性肺疾病、胃食管反流、类风湿关节炎等,共病的存在会导致支气管扩张患者住院及死亡风险增加,也导致医疗负担加重及治疗难度的加大。目前,对于共病的性质、患病率及对疾病严重程度和结果的影响知之甚少。加强对支气管扩张共病的研究,有助于更全面地评估患者病情及预后,也有助于简易、及时识别更为严重的支气管扩张患者,从而更好地对支气管扩张进行分层管理,最终改善患者的生活质量。

Bronchiectasis is characterized by chronic systemic inflammation,usually coexisting with complications,such as cardiovascular and cerebrovascular diseases,chronic obstructive pulmonary disease,gastroesophageal reflux,rheumatoid arthritis,etc.The presence of comorbidity will lead to increased risks of hospitalization and death of the patients,as well as increased medical burden and treatment difficulty.However,little is known about the nature and prevalence of the comorbidities and their impacts on the severity and outcome of the disease.Therefore,strengthening the research on bronchiectasis comorbidity is helpful for a more comprehensive assessment of the patient′s condition and prognosis,as well as for a simple and timely identification of the patients with more serious bronchiectasis,so as to better manage bronchiectasis by level,and finally improve the quality of life of the patients.