摘要
通过查阅历代本草及医书典籍,结合现代文献资料与实地考察对枸杞及地骨皮药材的名称、基原、药用部位、性味功效、产地、品质评价、采收加工、炮制进行本草考证,为包含该类药材的经典名方开发提供依据。历代本草文献记载枸杞的主流基原为枸杞Lycium chinense Mill.及宁夏枸杞L.barbarum L.,最早记载其产于河北,唐代确立甘州(今甘肃省张掖市)为枸杞道地产区并为历代认可,至清朝道地产区转移至宁夏地区。古代对枸杞子的性味认识由最初的苦、寒演变为甘、平,地骨皮则由早期的苦、大寒转为甘淡、寒。历代本草典籍记载枸杞子的炮制方式以酒浸为主,而地骨皮主流炮制方式则为甘草汤浸泡后焙干。基于考证结果,建议经典名方中涉及枸杞药材以宁夏枸杞L.barbarum为基原,地骨皮以枸杞L.chinense为基原,药用部位分别为果实、根皮,参考《中华人民共和国药典》规定进行炮制。
This study made a textual research on the name,origin,medicinal part,property and flavor,producing areas,quality evaluation,harvesting time and processing methods of Lycii Fructus and Lycii Cortex by referring to ancient Chinese herbs and medical books,combining with modern literature and on-the-spot investigation,and provided a basis for the development of the classic prescriptions containing those medicinal materials.The main basis of Lycii Fructus recorded in ancient Chinese materia medica was Lycium chinense Mill.and L.barbarum L.which was first recorded to be produced in Hebei province.In Tang Dynasty,Ganzhou became the genuine production area and was recognized by later generations.In Qing Dynasty,the genuine production area was transferred to Ningxia.The understanding of the property and flavor of Lycii Fructus changed from bitter and cold to sweet and neutral.The flavor of Lycii Cortex changed from bitter to slightly sweet.According to historical records,the main processing method of Lycii Fructus was wine soaking,while the main processing method of Lycii Cortex was liquorice soup soaking and baking.Based on the results of textual research,it is suggested that fruit of L.barbarum and root bark of L.chinense should be used as the source of Lycii Fructus and Lycii Cortex in the classical prescription,and the processing should refer to the Pharmacopoeia of the People′s Republic of China.
作者
赵佳琛
金艳
闫亚美
秦垦
钱丹
张卫
彭华胜
李兵
蔡秋杰
陈周全
杨洪军
张华敏
詹志来
ZHAO Jia-chen;JIN Yan;YAN Ya-mei;QIN Ken;QIAN Dan;ZHANG Wei;PENG Hua-sheng;LI Bing;CAI Qiu-jie;CHEN Zhou-quan;YANG Hong-jun;ZHANG Hua-min;ZHAN Zhi-lai(National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of Wolfberry Engineering Technology,Ningxia Academy of Agriculture and Forestry Sciences,Yinchuan 750002,China;Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Anhui University of Traditional Chinese Medicine,Hefei 230012,China;Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Research Center for Traditional Chinese Medicine Development,China Academy of Chinese Medical Sciences,Beijing 100700,China;China Resources Sanjiu Medical and Pharmaceutical Co.,Ltd.,Shenzhen 518029,China;China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《中国现代中药》
CAS
2020年第8期1269-1286,共18页
Modern Chinese Medicine
基金
宁夏回族自治区重点研发项目(2020BBF02006)
国家重点研发计划项目(2019YFC1711401,2017YFC1700805)
中央本级重大增减支项目(2060302)。
关键词
经典名方
枸杞
地骨皮
基原
道地
炮制
本草考证
classical prescriptions
Lycii Fructus
Lycii Cortex
origin
geoherbalism
processing methods
textual research on materia medica