肠内饲管给药对心力衰竭合并痛风患者预后的影响

Effects of enteral feeding tube on the prognosis of patients with heart failure and gout

目的探讨肠内饲管给药对心力衰竭(简称心衰)合并痛风患者预后的影响。方法选取2013年6月—2018年12月丽水市人民医院诊治的心衰合并痛风患者72例。按照随机数字表法分为对照组与观察组,每组36例。对照组在常规治疗外给予肠外支持治疗,观察组在常规治疗外给予肠内饲管给药治疗,记录两组预后。结果所有患者都顺利完成治疗,观察组的总有效率为100.0%,与对照组的88.9%比较,差异有统计学意义(P<0.05)。两组治疗后的血清尿酸浓度、C反应蛋白(CRP)与白细胞介素(IL-6)质量浓度都低于治疗前(P<0.05),观察组低于对照组(P<0.05)。两组治疗后的格拉斯哥昏迷指数(GCS)评分低于治疗前(P<0.05),两组治疗后的急性生理和慢性健康(APACHEⅡ)评分高于治疗前(P<0.05)。结论肠内饲管给药能抑制心衰合并痛风患者炎症因子与尿酸的释放,从而提高治疗效果,改善患者的预后。

Objective To investigate the effects of enteral feeding tube on the prognosis of patients with heart failure and gout.Methods From June 2013 to December 2018,72 patients with heart failure and gout were selected and treated in our hospital,and were divided into the observation group and the control group,36 cases in each group,accorded to the random number table method.The two groups were given conventional treatment.The control group were given parenteral support treatment,and the observation group were given enteral feeding tube treatment.The prognosis of the two groups were recorded.Results All patients were completed the treatment successfully.The total effective rates of the observation group were 100.0%,which were significantly higher than that of the control group 88.9%(P<0.05).The levels of serum uric acid,CRP and IL-6 in the two groups after treatment were significantly lower than those before treatment(P<0.05),and the observation group were also significantly lower than the control group(P<0.05).The GCS scores of the two groups after treatment were lower than those before treatment,and the APACHE II scores were also higher than before treatment(P<0.05).Conclusion The application of enteral feeding tube in patients with heart failure and gout can inhibit the release of inflammatory factors and uric acid,thereby improving the therapeutic effect and the prognosis of patients.