芍药甘草汤合自拟“润肠散”治疗阴虚肠燥型习惯性便秘的临床观察

Clinical observation of Shaoyao Gancao decoction combined with"Runchang powder"in treating habitual constipation of yin deficiency and Intestinal dryness

目的:探讨芍药甘草汤合自拟"润肠散"治疗阴虚肠燥型习惯性便秘的临床疗效,为其临床应用提供参考依据。方法:选择106例阴虚肠燥型习惯性便秘患者作为研究对象,采用随机数字法平均分为观察组53例及对照组53例。观察组给予芍药甘草汤合自拟"润肠散"治疗,对照组给予通便灵胶囊治疗。随访3个月,根据《中医病证诊断疗效标准》比较两组治疗前后中医证候总积分,同时记录便秘开始改善时间,并比较两组临床疗效。结果:治疗后观察组便秘改善时间为(1.12±0.23)天,明显早于对照组便秘改善时间(1.78±0.74)天,P <0.05;治疗后观察组中医证候总积分为(4.32±1.41)分,低于治疗前(15.43±5.43)分,P <0.05,且低于对照组治疗后中医证候总积分(7.33±0.73)分,P <0.05。观察组总有效率94.3%(50/53)明显高于对照组81.1%(43/53),P <0.05。结论:芍药甘草汤合自拟"润肠散"可明显改善阴虚肠燥型习惯性便秘的症状,更早的通便,且3个月总有效率高,复发率低,值得临床应用。

Objective:To explore the clinical effect of Shaoyao Gancao decoction(芍药甘草汤)combined with"Runchang powder"(润肠散)in treating habitual constipation of Yin deficiency and intestinal dryness.Methods:A total of 106 patients with habitual constipation of yin deficiency and intestinal dryness were selected as the research objects,and they were equally divided into 53 cases in the observation group and 53 cases in the control group by random number method.The observation group was given Shaoyao Gancao decoction combined with its own"Runchang powder"treatment,and the control group was given Tongbianling capsule.Followed up for 3 months,and compared the total scores of TCM syndromes before and after treatment according to the"Traditional Chinese Medicine Symptoms and Diagnostics Efficacy Criteria",while recording the time to start improvement of constipation,and comparing the clinical efficacy of the two groups.Results:The improvement time of constipation in the observation group after treatment was(1.12±0.23)days,which was significantly earlier than that of the control group(1.78±0.74)days(P<0.05).The total score of TCM syndromes in the observation group after treatment was(4.32±1.41).The score was lower than that before treatment(15.43±5.43)(P<0.05)and lower than the total score of TCM syndromes after treatment(7.33±0.73)(P<0.05).The total effective rate in the observation group was 94.3%(50/53),which was significantly higher than the control group's 81.1%(43/53)(P<0.05).Conclusion:Shaoyao Gancao decoction combined with“Runchang powder”can obviously improve the symptoms of habitual constipation of yin deficiency and intestinal dryness.It has an earlier laxative effect,and has a high total effective rate and low recurrence rate in March.