颅内肿瘤患者MRI影像学特征及其预后分析

MRI characteristics and prognosis in patients with intracranial tumors

目的探究颅内肿瘤患者MRI影像学特征及其预后分析。材料与方法选取2017年3月至2019年5月天门市第一人民医院收治的128例颅内肿瘤患者进行研究。同期130名体检健康者作为对照组。观察两组MRI影像学特征,颅内肿瘤患者治疗12周后评估其预后认知功能,并分析MRI影像学特征与认知功能的相关性。结果观察组蒙特利尔认知评估(Montreal Cognitive Assessment,MoCA)量表得分低于对照组,差异显著(P<0.05)。观察组MRI脑白质疏松1、2、3、4级分别为23.4%、26.6%、30.5%、19.5%,对照组MRI脑白质疏松1、2、3、4级分别为88.5%、10.0%、1.5%、0.0%,两组比较差异显著(P<0.05)。MRI显示瘤内血管流空所占比例为88.3%(113/128),瘤周水肿占65.6%(84/128),瘤内出血占84.4%(108/128),囊变坏死占76.6%(98/128)。经Pearson相关分析得到,MoCA评分与脑白质疏松、瘤内血管流空、瘤周水肿、瘤内出血、囊变坏死呈负相关(P<0.05)。结论MRI影像学分析得出颅内肿瘤患者影像学特征为脑白质疏松、瘤内血管流空、瘤周水肿、瘤内出血、囊变坏死,且上述现象越严重,表示预后认知功能越差。

Objective:To explore the MRI characteristics and prognosis of patients with intracranial tumors.Materials and Methods:A total of 128 patients with intracranial tumors admitted to the First People’s Hospital of Tianmen in Hubei Province from March 2017 to May 2019 were enrolled;meanwhile,130 healthy people were selected as the control group.The MRI features of the two groups were observed.The patients with intracranial tumors were evaluated for prognostic cognitive function after 12 weeks of treatment,and the correlation between MRI imaging features and cognitive function was analyzed.Results:The scores of the Montreal Cognitive Assessment scale(MoCA)in the observation group were lower than those in the control group(P<0.05).The MRI leukoaraiosis in level 1-4 in the observation group were 23.4%,26.6%,30.5%,19.5%,respectively;and those in the control group were 88.5%,10.0%,1.5%,0.0%,respectively(P<0.05).MRI showed that intratumoral vascular emptying accounted for 88.3%(113/128),peritumoral edema accounted for 65.6%(84/128),intratumoral bleeding accounted for 84.4%(108/128),and cystic necrosis accounted for 76.6%(98/128).According to Pearson correlation analysis,the MoCA score was negatively correlated with leukoaraiosis,intratumoral vascular emptying,peritumoral edema,intratumoral hemorrhage,and cystic necrosis(P<0.05).Conclusions:MRI imaging analysis showed that the imaging features of patients with intracranial tumors were leukoaraiosis,intratumoral vascular emptying,peritumoral edema,intratumoral hemorrhage,cystic necrosis;besides,the more serious the above phenomenon,the worse the cognitive function of prognosis.