磁共振功能成像在脑胶质瘤术后复发与假性进展鉴别诊断中的应用进展

Application progress of functional magnetic resonance imaging on differential diagnosis between tumor recurrence and pseudoprogression of gliomas

脑胶质瘤是成人中枢神经系统最常见的原发性恶性肿瘤,具有高侵袭性且预后差的特点。脑胶质瘤术后复发与假性进展的常规MRI均表现为新增强化灶或原强化灶扩大,但两者的治疗方法和预后截然不同,因此鉴别脑胶质瘤术后复发与假性进展仍然是临床面临的一大挑战。笔者就目前磁共振功能成像技术在评估脑胶质瘤术后复发与假性进展的应用研究予以综述。

Gliomas are the most common primary malignant brain tumors in adults with a dismal prognosis.The postoperative recurrence and pseudoprogression of gliomas may present with new and/or increasing enhancing mass lesions in conventional MRI.Differential diagnosis of glioma postoperative recurrence and pseudoprogression is still a major clinical challenge because management of these two entities is diametrically opposed.This article reviews the current research on the application of magnetic resonance imaging techniques in the evaluation of postoperative recurrence and pseudoprogression of gliomas.