基于磁共振图像影像组学对直肠癌新辅助放化疗疗效评估的研究进展

Research progress of neoadjuvant radiotherapy and chemotherapy for rectal cancer based on magnetic resonance imaging radiology

手术前的新辅助放化疗是局部进展期直肠癌标准的治疗模式,因此治疗前评估患者是否有良好的反应在临床中十分必要。常规MRI及功能成像在对患者的疗效预测中具有一定局限性,影像组学技术则可以通过高维特征提取来预测治疗反应,因此笔者分别对常规MRI和影像组学技术预测直肠癌患者新辅助放化疗疗效的方法和现状进行综述。

Neoadjuvant chemoradiotherapy followed by total mesorectal excision is the standard treatment for locally advanced rectal cancer,so it is necessary to evaluate whether patients have a good response before treatment.Quantify MRI and functional imaging have limitations in prediction of response,while radiomics can predict the treatment efficacy by highdimensional feature extraction.Therefore,this article reviews the methods and current status of quantify MRI andradiomics for predicting the efficacy of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.