冠状动脉造影结合血流储备分数对糖尿病合并冠心病介入治疗患者不良心血管事件发生率的影响

Impact of Coronary Angiography Combined with Fractional Flow Reserve on the Incidence of Adverse Cardiovascular Events in Interventional Therapy Patients with Diabetes Mellitus Complicated with Coronary Heart Disease

目的探讨CAG结合FFR对糖尿病合并冠心病介入治疗患者不良心血管事件发生率的影响。方法60例2型糖尿病合并冠心病患者随机均分为两组。对照组在CAG检查后行PCI常规植入药物洗脱支架(DES);研究组在CAG检测后行心肌FFR检测,对FFR≤0.80的患者植入DES。比较两组的治疗情况和不良心血管事件发生率。结果研究组的造影剂用量、支架植入数、住院时间及费用均显著低于对照组(P<0.05)。两组的不良心血管事件发生率无统计学差异(P>0.05)。结论CAG联合FFR可减少糖尿病合并冠心病介入治疗患者的造影剂用量及支架植入数,减少住院时间和费用,且不会增加不良心血管事件发生率。

Objective To explore the impact of CAG combined with FFR on the incidence of adverse cardiovascular events in interventional therapy patients with diabetes mellitus(DM)complicated with coronary heart disease(CHD).Methods 60 patients with type 2 DM complicated with CHD were randomly and equally divided into two groups.The control group underwent routine DES implantation through PCI after CAG examination;The study group received myocardial FFR test after CAG examination,and patients with FFR≤0.80 were given DES implantation.The treatment situation and incidence of adverse cardiovascular events were compared between two groups.Results The usage of contrast agent,number of stent implantation,hospitalization time and hospitalization cost of study group were significantly lower than those of control group(P<0.05).No statistical difference was found between two groups in the incidence of adverse cardiovascular events(P>0.05).Conclusions CAG combined with FFR can reduce the usage of contrast agent and the number of stent implantation in interventional therapy patients with DM complicated with CHD,reduce the hospitalization time and cost,and does not increase the incidence of adverse cardiovascular events.