丹参多酚酸盐联合曲克芦丁脑蛋白对老年急性脑梗死患者神经功能缺损、脑血流量的影响

Effect of Salvianolate Combined with Troxrutin Brain Protein on Neurological Deficit and Cerebral Blood Flow in Elderly Patients with Acute Cerebral Infarction

目的探讨丹参多酚酸盐联合曲克芦丁脑蛋白治疗老年急性脑梗死患者的临床效果。方法50例老年急性脑梗死患者随机分为两组各25例,对照组给予丹参多酚酸盐注射液治疗,观察组给予丹参多酚酸盐注射液联合曲克芦丁脑蛋白治疗。比较两组治疗前后的神经功能缺损(NIHSS)评分、脑血流量。结果治疗2周、4周后,两组的NIHSS评分均显著降低,且观察组显著低于对照组(P<0.05)。治疗后,两组的MCA、VA、BA、ECBF均显著升高,且观察组各指标均显著高于对照组(P<0.05)。结论丹参多酚酸盐联合曲克芦丁脑蛋白治疗急性脑梗死患者效果显著,可降低神经功能缺损程度,改善脑血流量。

Objective To explore the clinical effect of salvianolate combined with troxrutin brain protein in the treatment of elderly patients with acute cerebral infarction.Methods 50 elderly patients with acute cerebral infarction were randomly divided into two groups,with 25 cases in each group.The control group was treated with salvianolate injection,while the observation group was treated with salvianolate injection combined with troxrutin brain protein.The NIHSS score and cerebral blood flow before and after treatment were compared between two groups.Results After 2 weeks and 4 weeks of treatment,both groups had significantly decreased NIHSS score,and the NIHSS scores of observation group were significantly lower than those of control group(P<0.05).After treatment,both groups had significantly increased MCA,VA,BA and ECBF,and all the indicators of observation group were significantly higher than those of control group(P<0.05).Conclusions Salvianolate combined with troxrutin brain protein in the treatment of elderly patients with acute cerebral infarction has significant effect,which can reduce the degree of neurological deficit,and improve cerebral blood flow.