弱视患者发病机制及眼部结构的研究进展

Research progress on the pathogenesis and eye structure of amblyopic patients

弱视是一种儿童视觉发育关键期常见的眼科疾病,其发病机制复杂。传统观念认为弱视不会出现明显眼球器质性改变,但近年随着研究的深入,研究者们发现弱视患者不仅脑部解剖存在差异,在眼部结构也与正常人不尽相同,这为探索弱视发病机制提供了新的思路。本文就弱视患者的发病机制及眼部结构改变进行了总结,从发病机制、脉络膜厚度(CT)、眼部血管面积及密度、视网膜神经纤维层(RNFL)厚度以及弱视患者遮盖治疗后的眼部结构改变等方面进行综述。

Amblyopia is a common ophthalmic disease in the critical periodof children’s visual development,and its pathogenesis is complicated.The traditional idea is that amblyopia does not cause obvious changes in the organic structure of the eyeball.However,with the deepening of research in recent years,researchers have found that amblyopia patients not only have different brain anatomy,but also have different eye structure from normal people,which provides a new way to explore the pathogenesis of amblyopia.This paper summarized the pathogenesis and ocular structural changes of amblyopia patients,and summarized the pathogenesis,choroidal thickness(CT),ocular vascular area and density,retinal nerve fiber layer thickness(RNFL),and ocular structural changes after occlusion therapy in amblyopia patients.