广东省医疗机构新生儿科重症监护病房肠道病毒感染横断面风险监测

Cross-sectional risk monitoring of enterovirus infection in neonatal intensive care unit of medical institutions in Guangdong

目的了解广东省医疗机构新生儿科重症监护病房(NICU)医院感染预防与控制的实施效果,为科学评估医院感染暴发风险提供依据。方法通过横断面调查和卫生学监测方法,对全省283家医疗机构NICU医护工作人员手以及部分环境标本进行检测和肠道病毒进行荧光PCR检测分析。结果共采集不同类型标本10554份,肠道病毒核酸检测阳性率为0.35%,其中Echo11占比为37.84%。医护工作人员手,患儿排泄物,病区环境和物体表面以及水样等4类标本肠道病毒核酸阳性率分别为0.03%、3.13%、0.18%和0.21%。结论广东省医院NICU存在肠道病毒环境污染的情况,潜在幼儿肠道病毒医院感染暴发的风险,应加强风险管理目标和关键环节控制措施,以控制感染暴发的发生。

Objective To understand the implementation effect of prevention and control of nosocomial infection in the neonatal intensive care unit(NICU)of medical institutions in Guangdong,and to provide a basis for scientific assessment of the risk of nosocomial infection outbreak.Methods Through cross-sectional survey and hygiene monitoring methods,the hands of NICU medical staff in 283 medical institutions of the province and some environmental samples were tested,and enteroviruses were detected and analyzed by fluorescent PCR.Results A total of 10554 samples of different types were collected,and the positive rate of enterovirus nucleic acid detection was 0.35%,of which Echo11 accounted for 37.84%.The positive rates of enterovirus nucleic acid in four types of specimens including hands of medical staff,feces of children,environment and surface of objects in the ward,and water samples were 0.03%,3.13%,0.18%and 0.21%,respectively.Conclusion Enterovirus contamination was found in the environment of NICU in hospitals of Guangdong.There is a potential risk of nosocomial infection outbreak of enteroviruses in young children.Risk management objectives and critical points control measures should be strengthened to control the outbreak of infection.