氟比洛酚酯复合丙泊酚在无痛取卵术中的应用效果

Application effect of Flurbiprolol Ester combined with Propofol in painless transvaginal oocyte retrieval

目的观察氟比洛酚酯复合丙泊酚在无痛取卵术中的应用效果。方法选取2019年10~12月广东省计划生育专科医院收治的60例无痛取卵患者作为研究对象,按照随机数字表法将其分为氟比洛酚酯复合丙泊酚组(F组,30例)与丙泊酚组(B组,30例)。比较两组的丙泊酚总量、麻醉总时间、手术总时间、丙泊酚追加总量,术中体动次数、术后腹痛情况、术后不良反应情况。结果F组的丙泊酚总量、丙泊酚追加总量少于B组,差异有统计学意义(P<0.05);F组的麻醉总时间短于B组,差异有统计学意义(P<0.05),F组的术中体动情况发生率(10.0%)、术后腹痛情况发生率(6.7%),不良反应总发生率(23.3%)低于B组(23.3%,16.7%,46.7%),差异均有统计学意义(P<0.05)。结论氟比洛酚酯复合丙泊酚用于无痛取卵术,不但能减少丙泊酚总用量、丙泊酚追加总量、术中体动和术后不良反应发生率,同时能减少术后腹痛的发生率,缩短患者清醒时间,是一种相对安全、有效的方法。

Objective To observe the aapplication effect of Flurbiprolol Ester combined with Propofol in painless transvaginal oocyte retrieval.Methods A total of 60 patients in Family Planning Hospital of Guangdong Province from October to December 2019 were selected as the study subjects,and they were divided into Flurbiprolol Ester combined with Propofol group(group F,n=30)and Propofol group(group B,n=30)according to the random number table method.The total amount of Propofol,the total time duration of anesthesia,the total time of operation,the total amount of Propofol supplementation,the number of intraoperative body movements,postoperative abdominal pain and postoperative adverse reactions were compared between the two groups.Results The total amount of Propofol,the total amount of Propofol supplementation in the group F were lower than those in the group B,with statistical differences(P<0.05).The total time duration of anesthesia in the group F was shorter than that in the group B,with statistical difference(P<0.05).The number of intraoperative body movements(10.0%),postoperative abdominal pain(6.7%)and incidence of adverse events(23.3%)in the group F were lower than those in the group B(23.3%,16.7%,46.7%),with statistical differences(P<0.05).Conclusion Applicationc effect of Flurbiprolol Ester combined with Propofol in painless transvaginal oocyte retrieval is a relatively safe and effective method to reduce the total dosage of Propofol,the total amount of Propofol added,the body movement and respiratory inhibition,the incidence of postoperative abdominal pain,and shortening the patient waking hours.