持续性或复发性中心性浆液性脉络膜视网膜病变的危险因素分析

Risk factors for persistent or recurrent central serous chorioretinopathy

目的探讨持续性或复发性中心性浆液性脉络膜视网膜病变(CSC)的危险因素。方法回顾性分析2015年9月至2019年1月于徐州市第一人民医院收治的首次急性发作的CSC 150例(150只眼)患者的临床资料。根据患者出院后3个月内视网膜下液是否完全消退、且1年内是否复发分为观察组(持续性或复发性)和对照组(病情自限缓解)。采用多因素Logistic回归分析检验CSC持续或反复发作的危险因素。结果150例CSC患者中,对照组26例,观察组126例。多因素Logistic回归分析结果显示,男性、年龄≥50岁及失眠严重指数量表(ISI)评分≥14分为持续性或复发性CSC的独立危险因素(P<0.05)。结论男性、年龄≥50岁和ISI评分≥14分是CSC持续或反复发作的的独立危险因素,缓解睡眠障碍或许能改善患者的预后。

Objective To investigate risk factors for persistent or recurrent central serous chorioretinopathy(CSC).Methods The clinical data of 150 patients with first-onset CSC admitted to the Xuzhou First People's Hospital from September 2015 to January 2019 were retrospectively analyzed.The patients were divided into the observation group(persistent or recurrent)and the control group(self-limiting remission)according to whether the subretinal fluid completely subsided within 3 months after hospital discharge and relapse within 1 year.Multiple logistic regression analysis was used to examine the risk factors for persistent or recurrent CSC.Results Among the 150 CSC patients,26 were in the control group and 126 were in the observation group.Multiple logistic regression analysis showed that male gender,age≥50 years,and ISI score≥14 were independent risk factors for persistent or recurrent CSC(P<0.05).Conclusions Male gender,age≥50 years,and ISI score≥14 are independent risk factors for persistent or recurrent CSC.Relieving sleep disorders may improve patient prognosis.