摘要
冠状动脉微循环损伤是目前缺血性心脏疾病再灌注手术预后的重要风险因素之一。近年来的相关研究表明,评估冠状动脉微循环可以辅助诊断早期心脏供血类疾病或判断心肌缺血再通的预后情况,具有重要的临床意义。本文首先从病理生理学角度阐述了冠状动脉微循环及微循环损伤的定义,其次从工程学角度概述了若干影像学技术对冠状动脉微循环的探查方法及优劣,并提出了相关的研究展望。
Coronary microcirculation dysfunction(CMVD)is an important risk factor for the prognosis of reperfused ischemic heart.Recent studies showed that the evaluation of CMVD has significant impact on both the early diagnosis of heart diseases relevant to blood supply and prognosis after myocardial reperfusion.In this review,the definition of CMVD from the perspective of pathophysiology was clarified,the principles and features of the state-of-theart imaging technologies for CMVD assessment were reviewed from the perspective of engineering and the further research direction was promoted.
作者
刘博炜
吴艳芳
尹杰
肖晶晶
司东岳
林雪(综述)
丁海艳(审校)
LIU Bowei;WU Yanfang;YIN Jie;XIAO Jingjing;SI Dongyue;LIN Xue;DING Haiyan(Center for Biomedical Imaging Research(CBIR),Department of Biomedical Engineering,School of Medicine,Tsinghua University,Beijing 100084,P.R.China;Department of Cardiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,P.R.China;Department of Medical Engineering,Xinqiao Hosptial,The Army Medical University,Chongqing 400037,P.R.China)
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2020年第5期892-896,共5页
Journal of Biomedical Engineering
基金
国家重点研发计划(2016YFC0104700)
国家自然科学基金(61701506)。
