固尔苏治疗早产儿呼吸窘迫综合征的效果分析

Analysis of the effect of poractant alfa injection in the treatment of premature infants with respiratory distress syndrome

目的:分析固尔苏治疗早产儿呼吸窘迫综合征的效果。方法:2018年1月-2020年1月收治呼吸窘迫综合征早产儿44例,随机分为两组,各22例。对照组接受经鼻持续气道正压通气(NCPAP)治疗;观察组接受NCPAP联合固尔苏治疗。比较两组治疗效果。结果:观察组治疗总有效率高于对照组,且并发症发生率低于对照组,差异均有统计学意义(P<0.05)。观察组呼吸困难消失时间及氧疗时间均短于对照组,差异有统计学意义(P<0.05)。观察组治疗24 h后PEEP及FiO_2水平均低于对照组,差异有统计学意义(P<0.05)。结论:固尔苏治疗早产儿呼吸窘迫综合征的效果显著,并且可以缩短治疗时间,减少并发症发生率。

Objective:To analyze the effect of poractant alfa injection in the treatment of premature infants with respiratory distress syndrome.Methods:From January 2018 to January 2020,44 premature infants with respiratory distress syndrome were selected and they were randomly divided into the two groups,with 22 cases in each group.The control group received nasal continuous positive airway pressure ventilation(NCPAP).The observation group received NCPAP combined with poractant alfa injection.The therapeutic effects between the two groups was compared.Results:The total effective rate of treatment in the observation group was higher than the control group,and the incidence of complications was lower than the control group,with the differences were statistically significant(P<0.05).The duration of dyspnea and oxygen therapy in the observation group was shorter than the control group,with the differences were statistically significant(P<0.05).The levels of PEEP and FiO2 after treatment of 24 h in the observation group were lower than the control group,with the differences were statistically significant(P<0.05).Conclusion:Poractant alfa injection is effective in the treatment of premature infants respiratory distress syndrome,which can shorten the treatment time and reduce the incidence of complications.