320排动态容积CT双入口肺灌注扫描技术对原发性肺腺癌化疗近期效果的评估

Post-chemotherapy short-term evaluation of dual-input pulmonary perfusion with 320-slice dynamic volumetric CT in primary pulmonary adenocarcinoma

目的探讨320排动态容积CT双入口肺灌注扫描技术对肺腺癌化疗患者近期效果的评估价值。方法 50例中晚期原发性肺腺癌患者在化疗前及化疗后1个月接受320排动态容积CT双入口肺灌注检查,分析支气管动脉灌注值(BAF)、肺动脉灌注值(PAF)、灌注指数(PI)与疗效的关系。结果治疗前,缓解组PI值高于未缓解组,BAF值低于未缓解组(P<0.01或0.05)。治疗后,缓解组PAF和BAF值、未缓解组PI值均较治疗前下降(P<0.01或0.05)。结论 320排动态容积CT双入口肺灌注扫描成像技术有助于评估中晚期原发性肺腺癌化疗患者的近期效果。

Objective To evaluate the post-chemotherapy short-term role of dual-input pulmonary perfusion(DIPP)with 320-slice dynamic volumetric CT in primary pulmonary adenocarcinoma(PPAC).Methods Fifty patients with intermediate and advanced PPAC underwent DIPP with 320-slice dynamic volumetric CT before and 1 month after chemotherapy.The relationship between clinical efficacy and perfusion parameters including bronchial arterial flow(BAF),pulmonary arterial flow(PAF),and perfusion index(PI)was analyzed.Results Before treatment,PI was higher and BAF lower in remission group than in non-remission group(P<0.01 or 0.05).However,PAF and BAF in remission group and PI in non-remission group were decreased after treatment(P<0.01 or 0.05).Conclusion DIPP with 320-slice dynamic volumetric CT is helpful to evaluate the post-chemotherapy short-term efficacy in patients with intermediate and advanced PPAC.