帕瑞昔布钠导致配伍禁忌回顾性分析

Retrospective Analysis of Contraindications Caused by Parecoxib Sodium

目的:分析帕瑞昔布钠引起配伍禁忌的特点,为临床安全用药提供参考。方法:收集骨科2019年全年发生的帕瑞昔布钠出现配伍禁忌的完整资料,回顾性分析配伍禁忌的发生原因、物理化学表现以及主要处理措施。结果:帕瑞昔布钠出现配伍禁忌的主要原因为医师培训不足,主要理化表现为出现药液混浊或结晶沉淀,主要处理措施为停药、更换输液器以及更改医嘱。结论:应加强帕瑞昔布钠临床合理应用知识学习,确保临床用药安全。

Objective:To analyze the contraindications caused by parecoxib sodium and to provide references for clinical safe medication.Methods:Collect complete data on the contraindications of parecoxib sodium that occurred in the orthopedics department throughout 2019,and retrospectively analyze the causes,physical and chemical manifestations and main treatment measures of the contraindications.Results:The main reason for the contraindication of parecoxib sodium was insufficient training of physicians.The main physical and chemical manifestations were turbidity or crystal precipitation.The main treatment measures were stopping the drug,replacing the infusion set and changing the doctor's order.Conclusion:It is necessary to strengthen the knowledge of clinical rational application of parecoxib sodium to ensure the safety of clinical medication.