低剂量盐酸右美托咪定改善重症监护室老年患者睡眠质量的效果观察

Observation on the Effect of Dexmedetomidine Hydrochloride in Improving the Sleep Quality of Elderly Patients in Intensive Care Unit

目的:研究低剂量盐酸右美托咪定改善重症监护室老年患者睡眠质量。方法:选取2019年1—12月福鼎市总医院重症医学科收治的老年患者68例作为研究对象,随机分为对照组和观察组,每组34例。对照组患者提供江苏恩华药业有限公司生产的国药准字咪达唑仑药物治疗,观察组患者提供江苏恒瑞制药股份有限公司生产的盐酸右美托咪定,采用持续低剂量泵注镇静的方式,对患者进行治疗。比较2组患者提供不同的睡眠改善治疗方法,比较最终的结果。结果:经过治疗之后,观察组患者的睡眠质量评分从原本的(20.31±0.14)分提升至(42.31±0.66)分,睡眠结构中的睡眠效率、深睡眠期比率优于对照组,且整体满意度达到了94.12%,各项结果与对照组比较,差异有统计学意义(P<0.05)。结论:低剂量盐酸右美托咪定改善重症监护室老年患者睡眠质量有效。

Objective:To study the effect of dexmedetomidine hydrochloride on sleep quality in elderly patients in intensive care unit.Methods:A total of 68 elderly patients admitted to the Icu department of Fuding General Hospital from January 2019 to December 2019 were selected as study subjects and randomly divided into observation group and control group,with 34 patients in each group.Patients in the control group were provided with midazolam,a national drug approval drug,produced by Jiangsu Enhua Pharmaceutical Co.,LTD.,while patients in the observation group were provided with dexmedetomidine hydrochloride,produced by Jiangsu Hengrui Pharmaceutical Co.,LTD.,and treated by continuous low-dose pumping sedation.Compare the two groups of patients with different sleep improvement treatments and compare the final results.Results:After treatment,the sleep quality score of the patients in the observation group increased from(20.31±0.14)points to(42.31±0.66)points.The sleep efficiency and the ratio of deep sleep period in the sleep structure were better than the control group,and the overall satisfaction reached 94.12%.The differences between the results and the control group were statistically significant(P<0.05).Conclusion:Dexmedetomidine hydrochloride is effective in improving the sleep quality of elderly patients in intensive care unit.